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ACES Model

CHEMISTRY

Chemistry – Homeostasis Balance

The Chemistry of the ACES Model includes all the biochemical elements that keep the body alive—nutrients, hormones, neurotransmitters, inflammation, detoxification, the microbiome, and metabolic pathways. It represents the body’s internal laboratory, where food becomes fuel and signals, toxins create stress, and chemical balance determines energy, mood, immunity, and long-term health.

For Patients

Optimizing chemistry restores vitality, mood, and resilience.

For Clinicians

Treating biochemical balance addresses root causes, not just symptoms.

Evidence

What Does Science Show

Food & Nutrition

Provides the biochemical building blocks that fuel cellular function, balance hormones and neurotransmitters, regulate inflammation, and repair tissues. Proper nutrition stabilizes metabolism, supports detoxification, and directly influences energy, mood, immunity, and longevity.

Toxicity and Inflammation

Toxins overload the body’s systems, while chronic inflammation damages tissues and disrupts hormones, metabolism, and immunity. Together, they weaken all four ACES dimensions and block healing. Reducing toxicity and calming inflammation are essential steps to restoring balance and health.

Hormones & Neurotransmitters

They regulate mood, sleep, metabolism, stress response, immunity, and nearly every organ function. When these signals fall out of balance—whether from poor diet, stress, toxins, or inflammation—the entire ACES system becomes unstable. Restoring healthy hormonal and neurotransmitter balance is essential for clear thinking, emotional stability, metabolic health, and overall well-being.

Micronutrient deficiencies—such as of vitamin D, calcium, and vitamin K—are well-established contributors to chronic disease burden worldwide.

Afshin, A. et al.

Global Burden of Disease Study 2019 (GBD 2019)

Systemic inflammation and accumulated toxicants disrupt metabolic pathways, impair immune defense, and accelerate the development of chronic disease.

Furman, D. et al.

Nature Medicine (2019)

Hormonal and neurotransmitter imbalances disturb energy regulation, emotional stability, cognitive performance, and overall metabolic health.

McEwen, B.S.

Annual Review of Neuroscience (2007)
ACES Approach

How Does The ACES Model Manage It

Nutrition & diet

Nutraceutical & pharmacological therapy

Detox & Gut Health

ACES Framework

Structural integrity, movement, and alignment

Biochemical balance, nutrition, inflammation, hormones, and detoxification

Nervous system regulation, emotional flow, trauma healing, subtle forces

Meaning, identity, belief, forgiveness, spiritual wholeness

Anatomy

Structural Integrity

Chemistry

Biochemical Balance

Energy

Electrophysiology, Emotions

Soul

Consciousness, Purpose

The future of health and medicine

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